Efficient method for the synthesis of functionalized pyrazoles by catalyst-free one-pot tandem reaction of nitroalkenes with ethyl diazoacetate.
نویسندگان
چکیده
The one-pot synthesis of multisubstituted pyrazole derivatives was achieved via catalyst-free 1,3-dipolar cycloaddition of ethyl diazoacetate and nitroalkenes as the key step and elimination of the leaving group (NO(2) or Br) followed by intramolecular proton transfer with satisfactory yields.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 7 21 شماره
صفحات -
تاریخ انتشار 2009